Thanks to everyone who followed Training Because I Can! over the last nine years. This blog started with Addison's Disease, hypothyroidism and a crazy idea of doing an Ironman distance triathlon. My life has changed and so has this blog. I am using this blog strictly for Addison's Support topics from here on out. I hope to continue providing people with hints for living life well with adrenal insufficiency.
Saturday, August 1, 2009
July 30, 2009 — Women with a history of migraine had a 26% reduced risk for breast cancer, report researchers. The team is the first to explore the link between headache and breast-cancer risk, and these latest findings confirm their earlier study suggesting an association between the 2 hormonally mediated diseases. Both studies appear in the July issue of Cancer Epidemiology, Biomarkers & Prevention.
"This study is a lot larger than our first," lead investigator Christopher Li, MD, from the Fred Hutchinson Cancer Research Center, in Seattle, Washington, said in an interview. "We looked at more than 4500 cases and another 4500 controls. We had much more statistical power and found that the results were very consistent."
Medscape Neurology reported initial results in November. At that time, Dr. Li's team had looked at 3400 postmenopausal women. In this new study, researchers evaluated more patients, but also included premenopausal women.
"We were happy to see that we could replicate the finding and are encouraged by that," Dr. Li said. The group observed a similar reduced breast-cancer risk in this larger study.
Study participants were from the Women's Contraceptive and Reproductive Experiences Study, a population-based case-control trial. Women were age 35 to 64 years and had been diagnosed with invasive breast cancer.
Researchers attained migraine history from structured in-person interviews and found that women with a history of migraine had a reduced risk for breast cancer (odds ratio, 0.74; 95% CI, 0.66 – 0.82).
This risk did not differ by menopausal status, age at migraine diagnosis, or use of prescription medications. The risk was the same even when researchers restricted the analysis to women who avoided various migraine triggers such as alcohol, exogenous hormones, and smoking.
But the group cautions that it is also possible that medications used to treat or prevent migraine, rather than the occurrence of migraines, may be responsible for the reductions in risk.
Several studies of nonsteroidal anti-inflammatory drugs (NSAIDs) have shown that their use is associated with a reduced risk for breast cancer — especially hormone-receptor–positive tumors, the researchers note.
Dr. Li said that although this may explain part of the link, it is unlikely to be the only factor. A recent meta-analysis of studies of NSAID use and breast-cancer risk observed only a 12% reduction in risk for women who took an NSAID.
The biologic explanation behind the decreased risk is not known, but the researchers suspect that it has to do with fluctuations in levels of circulating hormones.
Fluctuations in Circulating Hormones
At the recent June meeting of the European Neurological Society in Milan, Italy, presenters pointed to an increased possibility of vascular risk factors in patients with migraine.
Presenter Hans-Christoph Diener, MD, from the University of Essen, in Germany encouraged neurologists to also test headache patients for cardiovascular risk factors.
Dr. Diener pointed to evidence suggesting that women who report migraine with aura are at particular risk. "We have to avoid myocardial infarction or stroke in people with migraine with aura," he said.
The discussion moved to hormonal factors when session moderator Jean Schoenen, MD, from the University of Liège, in Belgium, asked for more information about the risk of oral contraceptives in patients with migraine.
"If a patient has migraine with aura, takes the pill, and smokes, this is where I really get worried," Dr. Diener said. He emphasized that all patients should be encouraged to quit smoking.
Dr. Li told Medscape Neurology that his team did not have detailed enough data to assess migraine type but is contacting the women in the study to answer such questions. Investigators are planning a new study assessing the breast-cancer risk of patients with migraine with aura to see if they have a similar risk.
The researchers have disclosed no relevant financial relationships.
Cancer Epidemiol Biomarkers Prev. 2009;18:2030-2034.
Friday, July 31, 2009
July 29th, this is a summer morning in Idaho
I got 35 miles total of running in on Saturday and Sunday. I was only sore on my shin where I hit a hidden rock really hard.
I've sorted the pictures by subject so you can skip what you don't want to look at. Animals are at the bottom.
Click to see too many pictures of the most beautiful trail I've ever been on.
Mill Creek Trail
A view of the top of the Grand Teton through the Aspens. This is what you see from the Grand Teton Races course.
Red Creek Trail
Jo and Targhee on the new switchbacks on Red Creek Trail. Thanks Teton Valley Trails and Pathways!!
New culvert in the spring mud pit on Aspen Trail. My son helped Teton Valley Trails and Pathways put this culvert in. Yay Zane!
I love running in grizzly country
Yep, took this picture of myself. I'm a geek.
I thought I would take some cute video of me herding cows off the trail, instead I ended up hiding behind a tree because the "cow" turned out to be a bull that didn't want to be herded
Animals at the ranch
Catch getting his saddle removed
Godzilla on his new roost. Turkeys will probably be released pretty soon.
Baby horse is so cute and getting more beautiful every day.
Baby ducks are still a little weird, can't swim gracefully and stay together in a bunch.
Buffy's legs are getting better by the day. She is so much happier now.
Monday, July 27, 2009
I get so tired of hearing people say that they "can't". There are so many things we CAN do. If we can't, it means we're not trying hard enough or we're not asking for enough help. Make sure you ask your doctor if it's ok for your to make any changes to your daily routine.
Latest "I can't" annoyances.
- "I can't take my meds three or four times a day." There are some super simple ways to remember to take your meds through out the day. Get a pill organizer. Get a watch with multiple alarms. Set your cell phone alarms. Take your meds multiple times a day. You'll feel better. It's scientifically proven. Click here for links under Addison's Replacement Strategies.
- "I can't stop drinking diet soda." Don't buy it. It's bad for your bone density, it's bad for your gut, it's bad for your general health. It increases your chances of getting diabetes. "June 15, 2009 (Washington, DC) — People who use artificial sweeteners are heavier, more likely to have diabetes, and more likely to be insulin-resistant compared with nonusers, according to data presented here during ENDO 2009, the 91st annual meeting of The Endocrine Society."
- "I can't drink enough water throughout the day." Put a gallon jug full of the right amount of water for you in the fridge at the beginning of the day. Drink it throughout the day.
You can have good health, you have to start somewhere. Start with the above suggestions after you talk to your doctor. Please!